Pediatrics Postdoctoral Employee/Fellow - Nowicki Lab University of California Los Angeles
Requisition Number: JPF09975
We are seeking an experienced Ph.D. or M.D./Ph.D. for a post-doctoral fellowship in the laboratory of Dr. Theodore Scott Nowicki, M.D., Ph.D. Applicants need to have Ph.D in biosciences, an interest in cancer immunotherapy and immunology, and an interest in T-cell biology.
Dr. Nowicki is an Assistant Professor-in-Residence in the Department of Pediatrics (Division of Pediatric Hematology/Oncology), and the Department of Microbiology, Immunology, and Molecular Genetics. He is known for his studies of transgenic cellular immunotherapy/immune checkpoint blockade, functional epigenetics, DNA methylomics, and T-cell biology, with an emphasis in sarcomas and other solid tumors. Additionally, as a clinical specialist in pediatric oncology, Dr. Nowicki explores new and developing immunotherapies for pediatric sarcomas.
Qualifications:
Doctor of Philosophy in Biosciences, or related field of study <5 years from completion of PhD
Solid understanding of immunology/molecular biology and common laboratory approaches in immunology/molecular biology
Experience with murine models of adoptive cell therapy (tail-vein injection, intraperitoneal injection, phlebotomy, irradiation, splenocyte/T-cell isolation).
Ability to work simultaneously on multiple projects and quickly adapt to new tasks
Excellent communication skills and ability to work with computational and experimental scientists
Ability to function independently in the laboratory
Skills:
Conduct DNA, RNA and protein isolation and purification
Quantification of nucleic acids and proteins
Perform PCR, qPCR, ddPCR, ELISA and multiparametric flow cytometry to assist on-going specific research projects.
Culture adhered and non-adherent mammalian cells (T-cells), preparing media, aliquots and other compounds utilized in tissue culture with proper sterile aseptic technique.
Experience with murine models of adoptive cell therapy (tail-vein injection, intraperitoneal injection, phlebotomy, irradiation, splenocyte/T-cell isolation)
Experience with next-generation sequencing analysis (WES, RNAseq, WGBS, and ATAC-seq) is not required, but preferred.
May train and supervise less experienced research staff.
Duties/Responsibilities:
Conducting research as determined with Principal Investigator (PI)
Publish results of independent laboratory research in collaboration with lab PI, including writing of scientific manuscripts, abstracts and other supporting documentation
Participate in laboratory and Divisional seminars, meetings, educational sessions, general and specific safety training and other training sessions
Provide mentorship and teaching to other members of the lab which is comprised of PhD or MD students, post-docs, undergraduate students and summer students.
Pursue intramural and extramural funding opportunities to help fund current and future research endeavors.
Performs other duties and laboratory responsibilities as requested.
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